Tennessee Titans vs. Jaguars: Week 13 staff picks and predictions

The Tennessee Titans (1-10) will take on the Jacksonville Jaguars (7-4) this Sunday afternoon at Nissan Stadium in their 12th game of the 2025 regular season.

Opening the week, the Titans were listed as 7-point home underdogs, but that spread has softened slightly, with Jacksonville now at -6 as of this writing.

How does the Titans Wire staff see this Week 13 battle shaking out? Here's a look at our picks and score predictions.

Mark Mihalko: Jaguars 17, Titans 13

The Jaguars come to town for a tough AFC South battle, and the two teams slug it out in a defensive battle. Cam Ward continues to shine, keeping the Titans within striking distance, but they come up just short. Running back Travis Etienne finally wears down the Titans' defense, and Trevor Lawrence leads a fourth-quarter touchdown drive to close out the contest.

Serena Burks: Titans 24, Jaguars 23

The Titans and Jags have their first meeting this week, and it's going to be an interesting game. The Jags are 7-4, but they don't look like a 7-4 team. The Titans played the Seahawks pretty close in Week 12, and with the Jags' propensity to keep games close, Cam Ward & Co. can push through the gaps and get a win. The Titans have some momentum behind them after their attempted comeback, and even with the Jags' solid defense, I think the Titans can come away with their second win of the season with Cam Ward at the helm.

Dan Benton: Jaguars 27, Titans 16

The Jaguars have won three of their last four and are suddenly putting up points with the best offenses in football. The Titans, meanwhile, continue to steadily improve, but without the results to match. This will likely be another one of those games where they keep things close throughout, only to allow a back-breaking score at the end.

Bryan Manning: Jaguars 27, Titans 23

The Titans have lost six games in a row. The Jaguars sit at 7-4, and one game out of the AFC South lead. Jacksonville has proven to be streaky, and Tennessee looked feisty last week against a good Seattle team. Can the Titans break their losing streak? It will be close, but Jacksonville is simply the better team.

Tyler Henry: Jaguars 28, Titans 13

The Jaguars have won three of their last four and are averaging over 30 points per game in that span. I think the Titans' struggles will continue, and they will have a tough time slowing down the Jaguars in this one.

Joel Titus: Jaguars 27, Titans 24

Cam Ward and the passing game have truly arrived, and that will keep the rest of the Titans' games closer. However, the Jaguars are purely the better team, and they should just edge out the Titans out. The Jaguars have just enough talent to hold the Titans at bay and make them one-dimensional. I simply don’t trust the Titans' secondary enough to slow down the Jaguars' passing game, and that should be the difference.

This article originally appeared on Titans Wire: Tennessee Titans vs. Jaguars: Week 13 staff picks and predictions